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Research Projects

Sapienza supports research projects of significant scientific and technological interest.
The list of research projects of the Department is published below:

 

(2023)

PRINCIPAL INVESTIGATORTITLE
NENNA RAFFAELLANovel biomarkers for early disease monitoring through non-invasive analysis of saliva volatile organic compounds in pediatric diseases.
DE BERARDINIS EttorePhotodynamic Trans-Urethral Resection of Bladder Tumors (PDD-TURBT) to avoid Secondary Resections in Non-Muscle-Invasive Bladder Cancers (NMIBCs): the CUT-less Trial, a Phase IV, Non-Inferiority, Randomized Controlled Trial from "Sapienza" University of Rome
DI DONATO VIOLANTEApplication of artificial intelligence algorithms in the early detection and prevention of cervical cancer
PICCIONI Maria GraziaCorrelation between alcohol exposure in pregnancy and possible dysregulation of synthesis and release of neurotrophins, implicated in mechanisms of placentation and fetal neurodevelopment.
ZICARI Anna MariaDefining mucosal immunity induced by respiratory virus infection or vaccination: the influenza model
CECCANTI SILVIATHE EFFECT OF LAPAROSCOPIC PYLOROMYOTOMY ON CEREBRAL AND SPLANCHNIC OXYGENATION
GIANCOTTI AntonellaAspirin versus placebo for prevention of preeclampsia in twin pregnancy: a multicenter, randomized controlled trial
PALAIA INNOCENZAFrequency and management of preneoplastic lesions in BRCAm patients undergoing RRSO (Risk Reducing Salpingo Oophorectomy): an observational multicentric study.
PERNIOLA GIORGIA3D/4D Transperineal Ultrasound as innovative tool for the diagnosis of Chronic Pelvic Pain 
SALCICCIA STEFANOUrolithiasis and Metabolic syndrome (MET): prospective evaluation of MET traits impact on endoscopic post-operative outcomes and histopathological findings after simple nephrectomy in kidney stone formers

 

(2022)

PRINCIPAL INVESTIGATORTITLE
BOGANI GiorgioThe adoption of a deep learning-based diagnostic system for the detection of high-grade cervical lesions.
DI DONATO ViolanteRuolo della chirurgia robotica in ginecologia oncologica per il trattamento di pazienti fragili affette da carcinoma endometriale.
DI MASCIO DanieleRadiomic texture analysis and machine learning algorithms applied to first trimester ultrasound for predicting pregnancy outcome.
MARINO TAUSSIG DE BODONIA Bruno22q11.2 DELETION SYNDROME IN ADOLESCENCE AND ADULTHOOD: INTEGRATED MULTIDISCIPLINARY ASSESSMENT AND GENOMIC ARCHITECTURE STUDY.
MUZII LudovicoFollicle curettage at the time of oocyte pick-up in an IVF program: a randomized, double blinded clinical trial.
NENNA RaffaellaInfants with Bronchiolitis: role of inflammatory markers on respiratory function tests and respiratory outcome.
PICCIONI Maria GraziaValutazione dello stato neuro-infiammatorio attraverso il dosaggio delle neurotrofine su sangue materno, cordonale e su tessuto placentare: studio osservazionale di coorte su donne fumatrici in gravidanza.
PORPORA Maria GraziaIl dolore pelvico cronico: approccio multidisciplinare ed elaborazione di un algoritmo diagnostico.
SCIARRA AlessandroPROGNOSTIC VALUE OF PATHOGENETIC VARIANTS (PV) OF DDR GENES (DNA DAMAGE REPAIR) IN PATIENTS WITH A NEW DIAGNOSIS OF PROSTATIC CARCINOMA: IMPLICATION OF A HEREDITARY/FAMILIAL ANALYSIS.
TOMAO FedericaThe role of liquid biopsy associated to CT scan radiomics features in high grade serous ovarian carcinoma.

 

(2021)

PRINCIPAL INVESTIGATORTITLE
COZZI DenisMiniature apical axillary approach for repair of type C oesophageal atresia: a longitudinal and cross-sectional pilot study
MONTI MarcoTrattamento conservativo del carcinoma dell'endometrio in stadio iniziale in pazienti desiderose di prole e out-comes ostetrici: stato dell'arte e prospettive future.
PALAIA InnocenzaDanni collaterali da COVID-19: impatto del ritardo diagnostico-terapeutico in patologie ostetriche e ginecologiche e ruolo della telemedicina. 
PERNIOLA GiorgiaEndometrial cancer: comparison of ultrasound characteristics with histopathological and biomolecular patterns 
MARINO TAUSSIG DE BODONIA BrunoSindrome di Klinefelter in eta' pediatrica ed evolutiva: studio della funzione cardiaca e respiratoria, analisi multispecialistiche e correlazioni genotipo-fenotipo
NENNA RaffaellaImmune response in SARS-CoV-2 infected children. One-year longitudinal study on seroprevalence, neutralizing antibodies, cellular immunity and oxidative stress in a cohort of children and adolescents infected with COVID-19.
PORPORA Maria GraziaStudio multidisciplinare sul ruolo del sistema nervoso centrale e periferico nella patogenesi del dolore pelvico cronico in donne con endometriosi

 

(2020)

PRINCIPAL INVESTIGATORTITLE
DI DONATO ViolanteRadiOmics and Molecular classification in Endometrial cancer: development of a model to simplify therapy with precision medicine.
PACIFICO LuciaProspective evaluation of new biomarkers and imaging techniques such as multiparametric ultrasound for the diagnosis of non-alcoholic fatty liver disease (NAFLD) and its complications in youths
SCIARRA AlessandroEvaluation of serum thymidine kinase 1 (TK1) as a biomarker for follow-up and prediction of progression in early-stage and advanced prostate cancer patients
COZZI DenisCavectomy with or without reconstruction for Wilms' tumor with inferior vena cava involvement. 
FRANCO GiorgioTestis-sparing surgery for small testicular masses: safety and efficacy in a singlecentre study.
GIANCOTTI AntonellaIndicazione all'ecocardiografia fetale del primo trimestre: creazione di uno score ecografico per la stratificazione delle pazienti a rischio
MONTI MarcoTrattamento conservativo del carcinoma della cervice uterina in stadio iniziale e out-comes ostetrici: stato dell'arte e prospettive future.
MUZII LudovicoStudio prospettico sulla valutazione delle dimensioni dei noduli di endometriosi profonda e della sintomatologia dolorosa associata in pazienti infertili che si sottopongono ad induzione dell'ovulazione finalizzata alla Procreazione Medicalmente-Assistita (PMA).
NENNA RaffaellaEpidemiological surveillance study on respiratory viruses infections in the era of SARS-CoV-2 pandemic
PICCIONI Maria GraziaStoria riproduttiva nella donna portatrice di mutazione del gene BRCA1/2.